Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 7/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.39 |
| ▸ | SMAD2 | Q15796 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681813 | 0.78 | RIPK2 (0.38) | DYRK1AAPPKDM4ENPC1RAB9A | |
| SCHEMBL547703 | 0.75 | DYRK1A (0.49) | DYRK1AAPPRIPK1TGFBR1BMPR1A | |
| SCHEMBL3964625 | 0.73 | KDM4E (0.49) | APPKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL27972125 | 0.73 | DYRK1A (0.53) | DYRK1AAPPRIPK1KDM4ENPC1 | |
| SCHEMBL547334 | 0.72 | KDM4E (0.38) | KDM4ENPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL30302 | 0.72 | — | — | |
| SCHEMBL454744 | 0.72 | — | — | |
| SCHEMBL31214345 | 0.72 | DYRK1A (0.72) | DYRK1AAPPRIPK1KDM4ENPC1 | |
| SCHEMBL5544172 | 0.71 | ATP4A (0.60) | KDM4ENPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL447980 | 0.71 | APP (0.55) | DYRK1AAPPRIPK1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229977-A1 | COMPOSITIONS AND METHODS FOR BONDING GLUES, ADHESIVES, AND COATINGS TO SURFACES | University of Virginia Patent Foundation, D/B/A University of Virginia (US) | 2017-10-18 | — | — | EP | disclosed |