⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017054 | 0.61 | KDM4E (0.30) | — | |
| SCHEMBL49743 | 0.51 | MAOA (0.37) | — | |
| SCHEMBL8733374 | 0.50 | IDO1 (0.33) | — | |
| SCHEMBL895221 | 0.47 | — | — | |
| SCHEMBL399620 | 0.47 | — | — | |
| SCHEMBL18205013 | 0.45 | — | — | |
| SCHEMBL11218163 | 0.45 | ACHE (0.30) | — | |
| SCHEMBL15484301 | 0.44 | — | — | |
| P-Xylene SCHEMBL33600 | 0.44 | — | — | |
| SCHEMBL991281 | 0.43 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136774-A1 | Anti-Apoptotic Benzodiazepine Receptor Ligand Inhibitors | MALFROY-CAMINE BERNARD | 2011-06-09 | — | — | US | disclosed |
| US-20100120738-A1 | ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS | MALFROY-CAMINE BERNARD | 2010-05-13 | — | — | US | disclosed |
| US-7649091-B2 | complex comprising manganese acetate and {[{(Porphine-5,15-diyl)bis[cyclopropyl-diyl]}](2-)-N21,N22,N23, N24 }; reduce damage to cells; preventing or arresting free radical associated diseases or conditions; free radical scavengers | EUKARION, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| WO-2008033444-A2 | ANTI-APOPTOTIC BENZODIAZEPINE RECEPTOR LIGAND INHIBITORS | EUKARION, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| US-20060241095-A1 | Orally bioavailable low molecular weight metalloporphyrins as antioxidants | EUKARION, INC. | 2006-10-26 | — | — | US | disclosed |
| EP-1631572-A2 | ORALLY BIOAVAILABLE LOW MOLECULAR WEIGHT METALLOPORPHYRINS AS ANTIOXIDANTS | EUKARION, INC. (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2005000854-A2 | ORALLY BIOAVAILABLE LOW MOLECULAR WEIGHT METALLOPORPHYRINS AS ANTIOXIDANTS | EUKARION, INC. (US) | 2005-01-06 | — | — | WO | disclosed |