Prosulfuron

Prosulfuron

SCHEMBL19464005

CC(C)N(C(=O)COc1nnc(C(F)(F)F)s1)c1ccc(F)cc1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2CCC(F)(F)F)n1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flufenacet SCHEMBL19463450 0.90 MAPT (0.37) MAPTALDH1A1KDM4ENPC1GAA
Logran SCHEMBL19462948 0.88 MAPT (0.36) MAPTALDH1A1KDM4ENPC1GAA
Prosulfuron SCHEMBL29440211 0.79 MAPT (0.44) MAPTALDH1A1KDM4ENPC1GAA
Prosulfuron SCHEMBL56036 0.79 MAPT (0.44) MAPTALDH1A1KDM4ENPC1GAA
Prosulfuron SCHEMBL30298017 0.79 MAPT (0.44) MAPTALDH1A1KDM4ENPC1GAA
Trifloxysulfuron SCHEMBL6061945 0.75 GAA (0.42) GAA
Flufenacet SCHEMBL19463690 0.75 GAA (0.44) GAA
SCHEMBL9242425 0.75 MAPT (0.44) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL10383749 0.74 MAPT (0.46) MAPTALDH1A1KDM4ENPC1GAA
Flufenacet SCHEMBL4897219 0.74 MLYCD (0.34) MAPTALDH1A1MEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442962-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS Syngenta Participations AG (CH) 2019-02-20 EP disclosed
WO-2017178582-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2017-10-19 WO disclosed