SCHEMBL9242425

SCHEMBL9242425

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2CCC(C)(F)F)n1

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.44
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.43
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.35
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.33
CDK1 P06493 1/20 0.33
FBP1 P09467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prosulfuron SCHEMBL29440211 0.94 MAPT (0.44) MAPTALDH1A1KDM4ENPC1GAA
Prosulfuron SCHEMBL56036 0.94 MAPT (0.44) MAPTALDH1A1KDM4ENPC1GAA
Prosulfuron SCHEMBL30298017 0.94 MAPT (0.44) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL11341411 0.88 MAPT (0.45) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL10383749 0.88 MAPT (0.46) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL10680118 0.87 ALDH1A1 (0.45) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL6459389 0.87 ALDH1A1 (0.47) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL26761188 0.87 ALDH1A1 (0.53) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL11122289 0.86 ALDH1A1 (0.47) MAPTALDH1A1KDM4ENPC1GAA
SCHEMBL11047586 0.85 ALDH1A1 (0.46) MAPTALDH1A1KDM4ENPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0480871-B1 Synergistic agents and method for selective control of weeds CIBA GEIGY AG (CH) 1995-12-13 EP claimed
EP-0120814-B1 N-PHENYLSULFONYL-N'-PYRIMIDINYL- AND -TRIAZINYL UREA CIBA-GEIGY AG (CH) 1988-07-27 EP claimed
US-4671819-A FLUORO DERIVATIVES AS HERBICIDES; PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1987-06-09 US claimed
US-5310722-A Synergistic composition comprising a sulfonylurea and a thiadiazolo[3,4-a]py CIBA-GEIGY CORPORATION (US) 1994-05-10 US disclosed
US-4952726-A HERBICIDES, PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1990-08-28 US disclosed
US-4908467-A Certain fluoroalkylphenylsulfonamides CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed
US-4759793-A Herbicide for application in soybean crops CIBA-GEIGY CORPORTION (US) 1988-07-26 US disclosed
US-4671819-A FLUORO DERIVATIVES AS HERBICIDES; PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1987-06-09 US disclosed