Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 4/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.66 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26934885 | 1.00 | HSP90B1 (0.76) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19464935 | 1.00 | HSP90B1 (0.76) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL22933447 | 0.91 | HSP90B1 (0.62) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL25566630 | 0.89 | ADORA3 (0.75) | ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19459913 | 0.87 | HSP90B1 (0.80) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19799159 | 0.87 | HSP90B1 (0.80) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL22933142 | 0.86 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL25566633 | 0.86 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19464933 | 0.86 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19807386 | 0.86 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9789131-B1 | Compounds and methods for treating neurological and cardiovascular conditions | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-17 | — | — | US | disclosed |