Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 6/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.68 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464933 | 1.00 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19807386 | 1.00 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19799159 | 0.89 | HSP90B1 (0.80) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19459913 | 0.89 | HSP90B1 (0.80) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL25566633 | 0.88 | HSP90B1 (0.79) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19464932 | 0.86 | HSP90B1 (0.76) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19464935 | 0.86 | HSP90B1 (0.76) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL26934885 | 0.86 | HSP90B1 (0.76) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL19464995 | 0.85 | HSP90B1 (1.00) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 | |
| SCHEMBL22933144 | 0.85 | HSP90B1 (1.00) | HSP90B1ADORA3ADORA1ADORA2ATMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839615-B2 | Compounds and methods for treating addiction and related disorders | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210030760-A1 | COMPOUNDS AND METHODS FOR TREATING ADDICTION AND RELATED DISORDERS | ASTROCYTE PHARMACEUTICALS, INC. | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11839615-B2 | Compounds and methods for treating addiction and related disorders | ADORA2A, TAAR5, ADORA3 | HSP90B1 3592/4885ADORA3 3/4885ADORA1 11/4885 |
| US-20210030760-A1 | COMPOUNDS AND METHODS FOR TREATING ADDICTION AND RELATED DISORDERS | SLC6A3, PNMT, CES2 | HSP90B1 3289/4885ADORA3 274/4885ADORA1 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.