Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965491 | 0.85 | LMNA (0.31) | — | |
| SCHEMBL9965562 | 0.73 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL21597289 | 0.72 | MEN1 (0.32) | GAA | |
| SCHEMBL10959564 | 0.69 | PGK1 (0.34) | — | |
| SCHEMBL11452149 | 0.60 | GAA (0.66) | HTTPOLBGAAALDH1A1 | |
| SCHEMBL26546660 | 0.58 | HTT (0.35) | HTTPOLBGAAALDH1A1ELANE | |
| SCHEMBL13406299 | 0.58 | — | — | |
| SCHEMBL14228808 | 0.58 | — | — | |
| SCHEMBL5934061 | 0.56 | HTT (0.70) | HTTPOLBGAAALDH1A1ELANE | |
| SCHEMBL13208246 | 0.55 | GAA (0.58) | HTTPOLBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790229-B2 | Bruton's tyrosine kinase inhibitors | SUNESIS PHARMACEUTICALS, INC. (US) | 2017-10-17 | — | — | US | disclosed |