Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14329987 | 0.86 | KMT2A (0.55) | KMT2AMEN1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL30003710 | 0.82 | CYP1B1 (0.58) | KMT2AMEN1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL15886144 | 0.82 | CYP1B1 (0.58) | KMT2AMEN1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL21670093 | 0.82 | KMT2A (0.37) | KMT2AMEN1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL27805161 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL15383768 | 0.78 | MEN1 (0.57) | KMT2AMEN1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL30211961 | 0.78 | TYMS (0.51) | KMT2AMEN1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL28566950 | 0.77 | HEXA (0.57) | KMT2AMEN1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL14323672 | 0.77 | MEN1 (0.53) | KMT2AMEN1ALDH1A1KDM4EKEAP1 | |
| SCHEMBL16085321 | 0.76 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1KDM4EKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9791463-B2 | Methods for the selective detection of alkyne-presenting molecules and related compositions and systems | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2017-10-17 | — | — | US | disclosed |