Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19465787 | 0.86 | KMT2A (0.39) | KMT2AMEN1KEAP1NFE2L2KDM4E | |
| SCHEMBL15886144 | 0.85 | CYP1B1 (0.58) | KMT2AMEN1KEAP1NFE2L2KDM4E | |
| SCHEMBL30003710 | 0.85 | CYP1B1 (0.58) | KMT2AMEN1KEAP1NFE2L2KDM4E | |
| SCHEMBL21670093 | 0.84 | KMT2A (0.37) | KMT2AMEN1KEAP1NFE2L2KDM4E | |
| SCHEMBL15383768 | 0.83 | MEN1 (0.57) | KMT2AMEN1KEAP1NFE2L2KDM4E | |
| SCHEMBL27805161 | 0.83 | ALDH1A1 (0.44) | KMT2AMEN1KEAP1NFE2L2KDM4E | |
| SCHEMBL28566950 | 0.82 | HEXA (0.57) | KMT2AMEN1KEAP1NFE2L2KDM4E | |
| SCHEMBL14323672 | 0.82 | MEN1 (0.53) | KMT2AMEN1KEAP1NFE2L2KDM4E | |
| SCHEMBL30211961 | 0.80 | TYMS (0.51) | KMT2AMEN1KEAP1NFE2L2KDM4E | |
| SCHEMBL16085321 | 0.79 | ALDH1A1 (0.61) | KMT2AMEN1KEAP1NFE2L2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212189-B2 | Fluorescent probes for reactive sulfur species | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-15 | — | — | US | disclosed |
| US-20120329085-A1 | FLUORESCENT PROBES FOR REACTIVE SULFUR SPECIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329085-A1 | FLUORESCENT PROBES FOR REACTIVE SULFUR SPECIES | SQOR, CBS, CTH | KMT2A 4427/4885MEN1 3197/4885KEAP1 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.