Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPY4R | P50391 | 4/20 | 0.40 |
| ▸ | NPY1R | P25929 | 3/20 | 0.40 |
| ▸ | NPY2R | P49146 | 3/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19466325 | 1.00 | FURIN (0.42) | FURINTRPV1HTTKISS1RSMN1; SMN2 | |
| SCHEMBL16847753 | 0.91 | FURIN (0.43) | FURINHTTSMN1; SMN2CA1CA2 | |
| SCHEMBL22064590 | 0.91 | FURIN (0.51) | FURINHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22336348 | 0.89 | TRPV1 (0.44) | FURINTRPV1HTTNPY4RNPY1R | |
| SCHEMBL22336351 | 0.89 | TRPV1 (0.44) | FURINTRPV1HTTNPY4RNPY1R | |
| SCHEMBL26431147 | 0.89 | HTT (0.46) | FURINHTTSMN1; SMN2MAPTCA1 | |
| SCHEMBL23815045 | 0.89 | CHRND (0.44) | TRPV1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL19604294 | 0.88 | FURIN (0.41) | FURINHTTKISS1RSMN1; SMN2NPY4R | |
| SCHEMBL23344152 | 0.88 | FURIN (0.50) | FURINHTTSMN1; SMN2CA1CA2 | |
| SCHEMBL22266602 | 0.88 | ALB (0.43) | FURINHTTSMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790253-B2 | OSW-1 analogs and conjugates, and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-10-17 | — | — | US | disclosed |