Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22064590 | 0.97 | FURIN (0.51) | FURINHTTPTPN2PTPN1SIRT5 | |
| SCHEMBL16847753 | 0.89 | FURIN (0.43) | FURINHTTSIRT5SIRT1SIRT2 | |
| SCHEMBL19466303 | 0.88 | FURIN (0.42) | FURINHTTSMN1; SMN2CA1CA2 | |
| SCHEMBL19466325 | 0.88 | FURIN (0.42) | FURINHTTSMN1; SMN2CA1CA2 | |
| SCHEMBL27291528 | 0.88 | FURIN (0.49) | FURINHTTSIRT1SIRT2SIRT3 | |
| SCHEMBL20149172 | 0.87 | FURIN (0.49) | FURINHTTSIRT1SIRT2SIRT3 | |
| SCHEMBL26431147 | 0.87 | HTT (0.46) | FURINHTTSIRT5SIRT1SMN1; SMN2 | |
| SCHEMBL19591557 | 0.86 | FURIN (0.49) | FURINHTTSIRT1SIRT2 | |
| SCHEMBL27291530 | 0.86 | FURIN (0.51) | FURINHTTSMN1; SMN2TP53 | |
| SCHEMBL22266602 | 0.86 | ALB (0.43) | FURINHTTSIRT5SIRT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210138081-A1 | Amanitin Conjugates | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210138081-A1 | Amanitin Conjugates | CD47, MTX1, SIGLEC7 | FURIN 1247/4885HTT 852/4885PTPN2 3390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.