Tenilsetam

Tenilsetam

SCHEMBL194668

O=C1NCCNC1c1cccs1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 4/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 2/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
HTR2A P28223 3/20 0.38
HTR2C P28335 3/20 0.38
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
PKM P14618 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
LTK P29376 1/20 0.35
CDK5 Q00535 1/20 0.35
MST1R Q04912 1/20 0.35
DYRK1A Q13627 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9380187 0.74 HDAC8 (0.41) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL9379899 0.74 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL9693463 0.72 KDM4E (0.47) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL22815188 0.72 ALDH1A1 (0.40) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL3985924 0.70 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL27551235 0.70 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL26986647 0.69 PRCP (0.44) ALDH1A1KMT2AKDM4EMAPTHPGD
SCHEMBL596560 0.69 PRCP (0.44) ALDH1A1KMT2AKDM4EMAPTHPGD
SCHEMBL1823137 0.69 KDM4E (0.55) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL11903004 0.68 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210380952-A1 Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate UNIV PRINCETON (US) 2021-12-09 US claimed
EP-3656855-A1 METHOD TO PRODUCE VIRUS IN CULTURED CELLS The Trustees of Princeton University (US) 2020-05-27 EP claimed
EP-2699672-B1 METHOD TO PRODUCE VIRUS IN CULTURED CELLS UNIV PRINCETON (US) 2019-12-25 EP claimed
US-20190218524-A1 Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate THE TRUSTEES OF PRINCETON UNIVERSITY 2019-07-18 US claimed
US-20180298348-A1 Method to Produce Virus in Cultured Cells Supplemented With Alpha-Ketoglutarate UNIV PRINCETON (US) 2018-10-18 US claimed
US-9212349-B2 Method to produce virus in cultured cells THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-12-15 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20140113353-A1 Method to Produce Virus in Cultured Cells THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2014-04-24 US claimed
EP-2699672-A1 METHOD TO PRODUCE VIRUS IN CULTURED CELLS The Trustees of Princeton University (US) 2014-02-26 EP claimed
WO-2013158706-A1 METHOD TO PRODUCE VIRUS IN CULTURED CELLS SUPPLEMENTED WITH ALPHA-KETOGLUTARATE THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2013-10-24 WO claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060286046-A1 Skin care compositions HABER C ANDREW 2006-12-21 US claimed
WO-2006072175-A1 SKIN CARE COMPOSITIONS HABER DERMACEUTICS INC. (CA) 2006-07-13 WO claimed
EP-0759750-A4 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1998-05-27 EP claimed
EP-0759750-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO, Howard, K. (US) 1997-03-05 EP claimed
WO-1995031194-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1995-11-23 WO claimed
EP-0342536-B1 THIENYL-PIPERAZINONES, THEIR PREPARATION AND USE CASSELLA Aktiengesellschaft (DE) 1992-09-23 EP claimed
US-4898866-A NOOTROPIC AGENTS CASSELLA AKTIENGESELLSCHAFT (DE) 1990-02-06 US claimed
EP-0342536-A1 Thienyl-piperazinones, their preparation and use CASSELLA Aktiengesellschaft (DE) 1989-11-23 EP claimed