Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 3/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26986647 | 1.00 | PRCP (0.44) | PRCPGAAGLAKDM4EALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27849833 | 0.83 | GLA (0.39) | PRCPGAAGLAKDM4EALDH1A1 | |
| SCHEMBL27586954 | 0.82 | MAP4K1 (0.42) | GLAALDH1A1MAP4K1KMT2A | |
| SCHEMBL20304287 | 0.81 | DDB1 (0.40) | PRCPGAAKDM4EALDH1A1DDB1 | |
| SCHEMBL9786155 | 0.80 | TDP1 (0.50) | PRCPGAAKDM4EALDH1A1KDM1A | |
| SCHEMBL380027 | 0.80 | TDP1 (0.50) | PRCPGAAKDM4EALDH1A1KDM1A | |
| SCHEMBL1673497 | 0.80 | SLC6A3 (0.47) | PRCPALDH1A1KDM1AMAP4K1 | |
| SCHEMBL5586396 | 0.80 | SMN1; SMN2 (0.47) | PRCPALDH1A1GID4KDM1ARAB9A | |
| SCHEMBL17055320 | 0.80 | SMN1; SMN2 (0.42) | GAAKDM1ARAB9AMAP4K1MAPT | |
| SCHEMBL31049590 | 0.80 | MAP4K1 (0.41) | GLAALDH1A1MAP4K1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588715-A | Synthetic method for 1-methyl-3-phenylpiperazine | TAICANG YUNTONG BIOCHEMICAL ENGINEERING CO LTD | 2014-02-19 | — | — | CN | claimed |
| US-20250353852-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | KINETA INC (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4444316-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2024009283-A1 | AT2 ANTAGONISTS FOR NON-ADDICTIVE PAIN RELIEF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2023137634-A1 | TRICYCLIC COMPOUND, PREPARATION THEREFOR, PHARMACEUTICAL COMPOSITION AND USE | 上海奕拓医药科技有限责任公司 | 2023-07-27 | — | — | WO | disclosed |
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2023-07-20 | — | — | US | disclosed |
| WO-2023107557-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107557-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| CN-107174584-B | Application of piperazine structure-containing compound in preparation of LSD1 inhibitor | 福建金乐医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-07-07 | — | — | US | disclosed |
| WO-2002038552-A1 | A NOVEL METHOD FOR THE PREPARATION OF PIPERAZINE AND ITS DERIVATIVES | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2002-05-16 | — | — | WO | disclosed |
| WO-2001025219-A2 | PIPERAZINE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2001-04-12 | — | — | WO | disclosed |
| US-6051572-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME LTD. (GB) | 2000-04-18 | — | — | US | disclosed |
| WO-1997016445-A1 | AZETIDINE, PYRROLIDINE AND PIPERIDINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-09 | — | — | WO | disclosed |
| US-5326760-A | Aminobutanoic acid compounds having metalloprotease inhibiting properties | GLAXO, INC. (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1994000119-A1 | AMINOBUTANOIC ACID COMPOUNDS HAVING METALLOPROTEASE INHIBITING PROPERTIES | GLAXO INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| EP-0300074-A1 | Processes and intermediates useful in the preparation of Cis 1,3,4,6,7 llb-Hexa-hydro-7-aryl-2H-pyrazino[2,1-a]isoquinolines | PENNWALT CORPORATION (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4772705-A | Processes for the preparation of trans 1,3,4,6,7,11b-hexahydro-7-aryl-2H-pyrazinol[2,1-a]isoquinolines | PENNWALT CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4012389-A | ANTICOAGULANTS | DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) | 1977-03-15 | — | — | US | disclosed |
| US-3935214-A | ANTICOAGULANT | DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353852-A1 | COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE | PIKFYVE, TARDBP, TDP1 | PRCP 1287/4885GAA 1263/4885GLA 3037/4885 |
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | CD4, CRBN, GZMB | PRCP 726/4885GAA 2081/4885GLA 2986/4885 |
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | IDH1, IDH3B, IDH3A | PRCP 1576/4885GAA 141/4885GLA 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.