Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 3/20 | 0.48 |
| ▸ | MGLL | Q99685 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | GSDMD | P57764 | 2/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19468397 | 0.93 | PHGDH (0.46) | PHGDHMGLLALDH1A1LMNAHPGD | |
| SCHEMBL19494808 | 0.81 | PHGDH (0.34) | PHGDHMGLLALDH1A1ALDH2 | |
| SCHEMBL27702122 | 0.78 | PHGDH (0.52) | PHGDHMGLLALDH1A1LMNAHPGD | |
| SCHEMBL21221395 | 0.76 | MGLL (0.71) | PHGDHMGLLALDH1A1LMNAHPGD | |
| SCHEMBL9725688 | 0.76 | — | — | |
| SCHEMBL19468403 | 0.74 | MGLL (0.47) | PHGDHMGLLALDH1A1LMNAHPGD | |
| SCHEMBL11850426 | 0.72 | MGLL (0.65) | PHGDHMGLLALDH1A1LMNAHPGD | |
| SCHEMBL13652904 | 0.72 | MGLL (0.65) | PHGDHMGLLALDH1A1LMNAHPGD | |
| SCHEMBL19468230 | 0.71 | MGLL (0.44) | PHGDHMGLLALDH1A1LMNAHPGD | |
| SCHEMBL2145837 | 0.70 | MGLL (0.62) | PHGDHMGLLALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |
| EP-3235815-A1 | AGENTS AGAINST PARASITIC HELMINTHS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2017-10-25 | — | — | EP | disclosed |