Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.62 |
| ▸ | PHGDH | O43175 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.54 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | GSDMD | P57764 | 2/20 | 0.54 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21221395 | 0.87 | MGLL (0.71) | MGLLPHGDHALDH1A1LMNAHPGD | |
| SCHEMBL5965428 | 0.86 | MGLL (0.58) | MGLLPHGDHALDH1A1LMNAHPGD | |
| SCHEMBL13652904 | 0.83 | MGLL (0.65) | MGLLPHGDHALDH1A1LMNAHPGD | |
| SCHEMBL11850426 | 0.83 | MGLL (0.65) | MGLLPHGDHALDH1A1LMNAHPGD | |
| SCHEMBL9115859 | 0.79 | MGLL (0.60) | MGLLPHGDHALDH1A1LMNAHPGD | |
| SCHEMBL27668756 | 0.79 | MGLL (0.60) | MGLLPHGDHALDH1A1LMNAHPGD | |
| SCHEMBL23690700 | 0.77 | MGLL (0.58) | MGLLPHGDHALDH1A1LMNAHPGD | |
| SCHEMBL2242418 | 0.77 | ALDH1A1 (0.62) | MGLLPHGDHALDH1A1LMNAHPGD | |
| Ammonia Solution, Strong SCHEMBL28326734 | 0.77 | MGLL (0.58) | MGLLPHGDHALDH1A1LMNAHPGD | |
| SCHEMBL5972447 | 0.77 | MGLL (0.71) | MGLLPHGDHALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115738-A | Pyrazolylamino substituted quinazoles for the treatment of cancer | ASTRAZENECA AB (SE) | 2008-01-30 | — | — | CN | claimed |
| CN-110199219-A | Contact lenses monomer composition, contact lenses polymer and preparation method thereof and contact lenses and its manufacturing method | 日油株式会社 | 2019-09-03 | — | — | CN | disclosed |
| CN-103781460-B | Benefit agent delivery particles comprising dextran | UNILEVER NEDERLAND B.V. (NL) | 2016-05-18 | — | — | CN | disclosed |
| US-8772526-B2 | Method for preparing dithiocarbamates in particular from polyols of the glycerol type | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-08 | — | — | US | disclosed |
| US-8772526-B2 | Method for preparing dithiocarbamates in particular from polyols of the glycerol type | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-08 | — | — | US | disclosed |
| US-8772526-B2 | Method for preparing dithiocarbamates in particular from polyols of the glycerol type | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-08 | — | — | US | disclosed |
| CN-103781460-A | Benefit agent delivery particles comprising dextran | UNILEVER NV | 2014-05-07 | — | — | CN | disclosed |
| EP-2516390-B1 | METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE | CENTRE NAT RECH SCIENT (FR) | 2014-02-26 | — | — | EP | disclosed |
| EP-2516390-B1 | METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE | CENTRE NAT RECH SCIENT (FR) | 2014-02-26 | — | — | EP | disclosed |
| EP-2516390-A1 | METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE | Centre National de la Recherche Scientifique (FR) | 2012-10-31 | — | — | EP | disclosed |
| US-20120264941-A1 | METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-10-18 | — | — | US | disclosed |
| US-20120264941-A1 | METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-10-18 | — | — | US | disclosed |
| US-20120264941-A1 | METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-10-18 | — | — | US | disclosed |
| WO-2011083255-A1 | METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011083255-A1 | METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-07-14 | — | — | WO | disclosed |
| CN-101115738-A | Pyrazolylamino substituted quinazoles for the treatment of cancer | ASTRAZENECA AB (SE) | 2008-01-30 | — | — | CN | disclosed |
| US-4018611-A | Non-yellowing antimicrobial compositions comprising diiodomethyl sulfones | METALORGANA ETABLISSEMENT (FL) | 1977-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264941-A1 | METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE | CDS2, SGMS2, DGAT2 | MGLL 105/4885PHGDH 137/4885ALDH1A1 3514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.