SCHEMBL19469152

SCHEMBL19469152

Cc1cccc(C2=CC=C[CH]2)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.37
ATM Q13315 1/20 0.37
CNR2 P34972 1/20 0.33
NUDT1 P36639 3/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
P2RX7 Q99572 1/20 0.32
ADRB1 P08588 1/20 0.32
TSHR P16473 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TLR8 Q9NR97 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ACHE P22303 1/20 0.31
PIK3CD O00329 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19469140 0.83 TSHR (0.39) TSHRSMN1; SMN2CA1CA2CA7
SCHEMBL28216141 0.76 CYP2A6 (0.36) TRPA1ATMCYP1A2CYP2A6TSHR
SCHEMBL30834716 0.74 TRPA1 (0.52) TRPA1ATMCNR2NUDT1CYP1A2
SCHEMBL218508 0.74 TRPA1 (0.52) TRPA1ATMCNR2NUDT1CYP1A2
Hydrogen Sulfide SCHEMBL1538405 0.71 TRPA1 (0.50) TRPA1ATMCNR2NUDT1CYP1A2
Ammonia Solution, Strong SCHEMBL15862222 0.71 TRPA1 (0.50) TRPA1ATMCNR2NUDT1CYP1A2
Ammonia Solution, Strong SCHEMBL22444763 0.71 TRPA1 (0.50) TRPA1ATMCNR2NUDT1CYP1A2
SCHEMBL19838629 0.69 TRPA1 (0.48) TRPA1ATMCNR2NUDT1CYP1A2
SCHEMBL3692592 0.67 TRPA1 (0.46) TRPA1ATMNUDT1CYP1A2CYP2A6
SCHEMBL284410 0.67 TSHR (0.47) TRPA1ATMCYP1A2CYP2A6P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10604604-B2 Multimodal polyolefin resin, and molded body manufactured therefrom DAELIM INDUSTRIAL CO., LTD. (KR) 2020-03-31 US disclosed
US-20180305481-A1 MULTIMODAL POLYOLEFIN RESIN, AND MOLDED BODY MANUFACTURED THEREFROM DL CHEMICAL CO., LTD. (KR) 2018-10-25 US disclosed
EP-3369752-A1 MULTIMODAL POLYOLEFIN RESIN, AND MOLDED BODY MANUFACTURED THEREFROM Daelim Industrial Co., Ltd. (KR) 2018-09-05 EP disclosed
US-9975977-B2 Multimodal polyolefin resin having high melt strength and molded product prepared with the same DAELIM INDUSTRIAL CO., LTD. (KR) 2018-05-22 US disclosed
EP-3239196-A1 MULTIMODAL POLYOLEFIN RESIN HAVING HIGH MELT STRENGTH AND MOLDED PRODUCT PREPARED WITH THE SAME Daelim Industrial Co., Ltd (KR) 2017-11-01 EP disclosed
US-20170306069-A1 MULTIMODAL POLYOLEFIN RESIN HAVING HIGH MELT STRENGTH AND MOLDED PRODUCT PREPARED WITH THE SAME DL CHEMICAL CO., LTD. (KR) 2017-10-26 US disclosed