SCHEMBL194708

SCHEMBL194708

Nn1[nH]c(=O)c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.42
PARP1 P09874 2/20 0.38
DAO P14920 1/20 0.38
CYP1A2 P05177 1/20 0.38
GSK3B P49841 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CHEK1 O14757 1/20 0.37
FYN P06241 1/20 0.37
PDGFRB P09619 1/20 0.37
PIM1 P11309 1/20 0.37
FGFR1 P11362 1/20 0.37
GRK5 P34947 1/20 0.37
KDR P35968 1/20 0.37
MAP2K2 P36507 1/20 0.37
MAPK8 P45983 1/20 0.37
CDK8 P49336 1/20 0.37
GSK3A P49840 1/20 0.37
NEK2 P51955 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL189858 0.78 KDM4E (0.59) KDM4ETP53TSHRPARP1CYP1A2
SCHEMBL29930611 0.78 KDM4E (0.59) KDM4ETP53TSHRPARP1CYP1A2
SCHEMBL1316368 0.77 KDM4E (0.57) KDM4ETP53TSHRPARP1CYP1A2
SCHEMBL1316369 0.77 KDM4E (0.57) KDM4ETP53TSHRPARP1CYP1A2
SCHEMBL30839913 0.76 KDM4E (0.45) KDM4ETP53TSHRPARP1DAO
SCHEMBL2270654 0.74 KDM4E (0.64) KDM4ETP53TSHRPARP1DAO
SCHEMBL29845563 0.74 KDM4E (0.64) KDM4ETP53TSHRPARP1DAO
SCHEMBL13488073 0.74 KDM4E (0.44) KDM4ETP53TSHRPARP1DAO
SCHEMBL10969803 0.71 TSHR (0.69) KDM4ETP53TSHRCYP1A2GAA
SCHEMBL2270985 0.71 TP53 (0.46) KDM4ETP53TSHRPARP1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024120884-A1 AROMATIC AMINE MODIFIED ACID-OLEFIN COPOLYMER FOR LUBRICANTS BASF SE (DE) 2024-06-13 WO claimed
CN-109705956-B Dispersant viscosity index improvers for enhanced wear protection of engine oils 雅富顿化学公司 2022-05-27 CN claimed
CN-108291171-B Synergistic lubricating oil composition containing mixture of olefin copolymer dispersant type viscosity improver and amine compound 雪佛龙奥伦耐有限责任公司 2022-02-01 CN claimed
EP-3555246-B1 MULTI-FUNCTIONAL OLEFIN COPOLYMERS AND LUBRICATING COMPOSITIONS CONTAINING SAME AFTON CHEMICAL CORP (US) 2020-11-25 EP claimed
EP-3405554-B1 LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF OLEFIN COPOLYMER DISPERSANT-TYPE VISCOSITY IMPROVER AND AMINE COMPOUND CHEVRON ORONITE CO (US) 2019-12-25 EP claimed
EP-3555246-A1 MULTI-FUNCTIONAL OLEFIN COPOLYMERS AND LUBRICATING COMPOSITIONS CONTAINING SAME Afton Chemical Corporation (US) 2019-10-23 EP claimed
US-10414999-B2 Synergistic lubricating oil composition containing a mixture of olefin copolymer dispersant-type viscosity improver and amine compound CHEVRON ORONITE COMPANY LLC (US) 2019-09-17 US claimed
EP-1807455-B1 METHOD FOR PREPARING AN IMIDIZED POLYMER Arlanxeo Netherlands Bv (NL) 2019-04-03 EP claimed
US-10190070-B2 Multiple-function dispersant graft polymer CASTROL LIMITED (GB) 2019-01-29 US claimed
EP-1686141-B1 Grafted multi-functional olefin copolymer and uses thereof AFTON CHEMICAL CORP (US) 2018-12-26 EP claimed
EP-0465031-A1 Multifunctional viscosity index improvers TEXACO DEVELOPMENT CORPORATION (US) 1992-01-08 EP claimed
US-5075383-A Graft and amine derivatized copolymer of ethyleneand alpha olefin TEXACO INC. (US) 1991-12-24 US claimed
US-5013469-A Butylene-ethylene-styrene polymer reacted with maleic anhydride and aromatic polyamine TEXACO INC. (US) 1991-05-07 US claimed
US-5013468-A Terpolymer of aminoalkyl acrylamide or acrylate, an acrylamide and an acrylate TEXACO INC. (US) 1991-05-07 US claimed
US-5013470-A Antioxidant VII lubricant additive TEXACO INC. (US) 1991-05-07 US claimed
US-4999267-A ELECTROGRAPHY MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1991-03-12 US claimed
EP-0414343-A1 VI improver, dispersant, and anti-oxidant additive and lubricating oil composition containing same TEXACO DEVELOPMENT CORPORATION (US) 1991-02-27 EP claimed
EP-0396297-A2 Dispersant - anti-oxidant additive and lubricating oil composition containing same TEXACO DEVELOPMENT CORPORATION (US) 1990-11-07 EP claimed
EP-0338672-A1 Viscosity index improver, dispersant and anti-oxidant additive and lubricating oil composition containing same TEXACO DEVELOPMENT CORPORATION (US) 1989-10-25 EP claimed
US-4863623-A VISCOSITY INDEX, GRAFT POLYMERS OF ETHYLENE MODIFIED WITH AMINE COMPOUND TEXACO INC. (US) 1989-09-05 US claimed