Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.48 |
| ▸ | MC4R | P32245 | 2/20 | 0.48 |
| ▸ | MC3R | P41968 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 1/20 | 0.44 |
| ▸ | TSLP | Q969D9 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19473957 | 0.93 | SIRT2 (0.49) | SIRT2SIRT1SIRT3MC4RMC3R | |
| SCHEMBL19473904 | 0.92 | MC4R (0.46) | SIRT2SIRT1SIRT3MC4RMC3R | |
| SCHEMBL18717178 | 0.90 | SIRT2 (0.47) | SIRT2SIRT1SIRT3MC4RMC3R | |
| SCHEMBL18716997 | 0.89 | MC4R (0.53) | SIRT2SIRT1SIRT3MC4RMC3R | |
| SCHEMBL19473945 | 0.88 | MC4R (0.48) | SIRT2SIRT1SIRT3MC4RMC3R | |
| SCHEMBL19474012 | 0.87 | MC4R (0.45) | SIRT2SIRT1SIRT3MC4RMC3R | |
| SCHEMBL18717171 | 0.87 | MC4R (0.47) | SIRT2SIRT1SIRT3MC4RMC3R | |
| SCHEMBL18717187 | 0.86 | MC4R (0.59) | MC4RMC3RTSLP | |
| SCHEMBL19473798 | 0.86 | MC4R (0.47) | SIRT2SIRT1SIRT3MC4RMC3R | |
| SCHEMBL20206246 | 0.86 | CTSG (0.46) | SIRT2SIRT1SIRT3MC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440227-B1 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | PALATIN TECHNOLOGIES INC (US) | 2017-10-18 | — | — | EP | disclosed |