SCHEMBL19474377

SCHEMBL19474377

C1=CCCC(c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc5c6ccccc6n(-c6ccc(-c7ccccc7)cc6)c5cc43)n2)=C1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HDAC4 P56524 1/20 0.31
PTGER4 P35408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26146823 0.93 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL19636294 0.93 KDM4E (0.38) KDM4EATML3MBTL1PTGER4
SCHEMBL19452438 0.91 L3MBTL1 (0.41) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL26059391 0.89
SCHEMBL19452299 0.87 L3MBTL1 (0.41) KDM4EATML3MBTL1HDAC4
SCHEMBL21599330 0.87 PTGER4 (0.32) KDM4EATML3MBTL1PTGER4
SCHEMBL26057161 0.86 ALDH1A1 (0.32) KDM4EL3MBTL1
SCHEMBL19452658 0.86 KDM4E (0.36) KDM4EATML3MBTL1PTGER4
SCHEMBL12675730 0.85 PTGER4 (0.33) KDM4EATML3MBTL1PTGER4
SCHEMBL16521267 0.85 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2866273-B1 Organic electrolumiescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-10-18 EP disclosed