SCHEMBL194744

SCHEMBL194744

CC(=O)c1ccc(Sc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 1.00
ALDH1A1 P00352 1/20 1.00
LMNA P02545 2/20 0.83
L3MBTL1 Q9Y468 1/20 0.83
MAPT P10636 4/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
CTSK P43235 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MAOB P27338 1/20 0.46
EZH2 Q15910 1/20 0.45
KMT2A Q03164 1/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
KIF11 P52732 1/20 0.44
HSD17B1 P14061 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10870776 1.00 HPGD (1.00) HPGDALDH1A1LMNAL3MBTL1MAPT
SCHEMBL10871888 0.94 HPGD (0.89) HPGDALDH1A1LMNAL3MBTL1MAPT
SCHEMBL10871219 0.94 HPGD (0.89) HPGDALDH1A1LMNAL3MBTL1MAPT
SCHEMBL12256962 0.94 HPGD (0.89) HPGDALDH1A1LMNAL3MBTL1MAPT
SCHEMBL1755726 0.91 HPGD (1.00) HPGDALDH1A1LMNAL3MBTL1MAPT
SCHEMBL835108 0.91 HPGD (1.00) HPGDALDH1A1LMNAL3MBTL1MAPT
SCHEMBL13398131 0.90 HPGD (0.81) HPGDALDH1A1LMNAL3MBTL1MAPT
SCHEMBL10873840 0.89 HPGD (0.79) HPGDALDH1A1LMNAL3MBTL1MAPT
SCHEMBL10873836 0.89 HPGD (0.79) HPGDALDH1A1LMNAL3MBTL1MAPT
SCHEMBL10872100 0.89 HPGD (0.79) HPGDALDH1A1LMNAL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 610 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118119253-A Composite material, preparation method thereof and light-emitting device 广东聚华新型显示研究院 2024-05-31 CN claimed
CN-110922346-A Tris (4-acetyldiphenyl sulfide) thioylium hexafluorophosphate and synthesis method thereof 上海鑫响实业有限公司 2020-03-27 CN claimed
US-7375144-B2 Abrasion resistant coatings EASTMAN CHEMICAL COMPANY (US) 2008-05-20 US claimed
EP-1891169-A1 ABRASION RESISTANT COATINGS EASTMAN CHEMICAL COMPANY (US) 2008-02-27 EP claimed
WO-2006138198-A1 ABRASION RESISTANT COATINGS EASTMAN CHEMICAL COMPANY (US) 2006-12-28 WO claimed
US-20060286383-A1 ABRASION RESISTANT COATINGS EASTMAN CHEMICAL COMPANY (US) 2006-12-21 US claimed
CN-122080822-A Pressure-sensitive epoxy adhesive composition and preparation method and application thereof 2026-05-26 CN disclosed
US-20260079397-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, AND METHOD FOR PRODUCING CURED PRODUCT TORAY INDUSTRIES, INC. (JP) 2026-03-19 US disclosed
CN-121338770-A Catalyst for preparing 4-acetyl diphenyl sulfide and application thereof 湖北远大富驰医药化工股份有限公司 2026-01-16 CN disclosed
CN-121338770-A Catalyst for preparing 4-acetyl diphenyl sulfide and application thereof 湖北远大富驰医药化工股份有限公司 2026-01-16 CN disclosed
US-12264120-B2 Amine synergists with UV—a absorption SUN CHEMICAL CORPORATION (US) 2025-04-01 US disclosed
EP-4301725-B1 AMINE SYNERGISTS WITH UV-A ABSORPTION SUN CHEMICAL CORP (US) 2024-08-21 EP disclosed
US-20240270678-A1 AMINE SYNERGISTS WITH UV-A ABSORPTION SUN CHEMICAL CORPORATION (US) 2024-08-15 US disclosed
US-4968702-A ANTIARTHRITIC, INHIBITORS OF PROGRESSIVE JOINT DETERIORATION, IMMUNOSUPPRESSANT AMERICAN CYANAMID COMPANY (US) 1990-11-06 US disclosed
EP-0379145-A2 Substituted quinolinecarboxylic acids AMERICAN CYANAMID COMPANY (US) 1990-07-25 EP disclosed
EP-0192167-A1 Use of thio-substitued ketones as photoinitiators MERCK PATENT GmbH (DE) 1986-08-27 EP disclosed
US-4536517-A ANTIDIABETIC, ANTILIPEMIC AGENTS AMERICAN CYANAMID COMPANY (US) 1985-08-20 US disclosed
US-4251341-A DIALKOXY-ACETYL DERIVATIVES OF AROMATIC COMPOUNDS CIBA-GEIGY CORPORATION (US) 1981-02-17 US disclosed
US-4055652-A 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof SYNTEX (U.S.A.) INC. (US) 1977-10-25 US disclosed
US-3933793-A BACTERICIDES, VIRICIDES RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12264120-B2 Amine synergists with UV—a absorption OR51E2, PNMT, ALDH7A1 HPGD 377/4885ALDH1A1 11/4885LMNA 2858/4885
US-20240270678-A1 AMINE SYNERGISTS WITH UV-A ABSORPTION ALDH7A1, PNMT, OR51E2 HPGD 355/4885ALDH1A1 8/4885LMNA 2210/4885
US-20260079397-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, AND METHOD FOR PRODUCING CURED PRODUCT PPA1, PHOSPHO1, PHPT1 HPGD 2876/4885ALDH1A1 637/4885LMNA 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.