Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19474989 | 1.00 | GPR84 (0.53) | GPR84FFAR1FAAHSOAT1MEN1 | |
| SCHEMBL5974006 | 0.89 | FAAH (0.59) | GPR84FFAR1FAAHSOAT1MEN1 | |
| SCHEMBL29634344 | 0.89 | FAAH (0.59) | GPR84FFAR1FAAHSOAT1MEN1 | |
| SCHEMBL10481737 | 0.89 | FAAH (0.59) | GPR84FFAR1FAAHSOAT1MEN1 | |
| SCHEMBL6748934 | 0.89 | FAAH (0.59) | GPR84FFAR1FAAHSOAT1MEN1 | |
| SCHEMBL7854038 | 0.89 | FAAH (0.59) | GPR84FFAR1FAAHSOAT1MEN1 | |
| SCHEMBL7854030 | 0.89 | FAAH (0.59) | GPR84FFAR1FAAHSOAT1MEN1 | |
| SCHEMBL6748929 | 0.89 | FAAH (0.59) | GPR84FFAR1FAAHSOAT1MEN1 | |
| SCHEMBL6897483 | 0.89 | FAAH (0.59) | GPR84FFAR1FAAHSOAT1MEN1 | |
| SCHEMBL15007874 | 0.89 | GPR84 (0.65) | GPR84FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | claimed |
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |