Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17652072 | 0.84 | TDP1 (0.56) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL5076356 | 0.84 | TDP1 (0.56) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL1062711 | 0.84 | TDP1 (0.56) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL20346213 | 0.75 | TDP1 (0.45) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL4608055 | 0.69 | TDP1 (0.43) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL8996568 | 0.68 | TDP1 (0.41) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL8731646 | 0.68 | TDP1 (0.42) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL10949610 | 0.68 | TDP1 (0.45) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL8618809 | 0.64 | TDP1 (0.48) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL31633234 | 0.64 | TDP1 (0.38) | TDP1POLBALDH1A1CTDSP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135774-A1 | BIOMOLECULE PROCESSING FROM FIXED BIOLOGICAL SAMPLES | CELL DATA SCIENCES, INC. (US) | 2019-05-09 | — | — | US | disclosed |
| WO-2017184984-A1 | BIOMOLECULE PROCESSING FROM FIXED BIOLOGICAL SAMPLES | CELL DATA SCIENCES, INC. (US) | 2017-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135774-A1 | BIOMOLECULE PROCESSING FROM FIXED BIOLOGICAL SAMPLES | UNG, POLN, POLB | TDP1 292/4885POLB 3/4885ALDH1A1 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.