Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17652072 | 1.00 | TDP1 (0.56) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL1062711 | 1.00 | TDP1 (0.56) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL20346213 | 0.87 | TDP1 (0.45) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL4608055 | 0.84 | TDP1 (0.43) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL19475130 | 0.84 | TDP1 (0.42) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL8731646 | 0.83 | TDP1 (0.42) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL10949610 | 0.83 | TDP1 (0.45) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL8996568 | 0.81 | TDP1 (0.41) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL31633234 | 0.77 | TDP1 (0.38) | TDP1POLBALDH1A1CTDSP1MEN1 | |
| SCHEMBL8725980 | 0.77 | TDP1 (0.52) | TDP1POLBALDH1A1CTDSP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446284-B1 | INFUSION OF CYCLIC OLEFIN RESINS INTO POROUS MATERIALS | MATERIA INC (US) | 2008-10-01 | — | — | EP | disclosed |
| EP-1185869-B1 | LIGAND-ANCHOR CONJUGATES FOR PRODUCING A BIOSENSOR LAYER | GRAFFINITY PHARMACEUTICALS AG (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20060052487-A1 | Infusion of cyclic olefin resins into porous materials | MATERIA INC. | 2006-03-09 | — | — | US | disclosed |
| US-20030186035-A1 | Infusion of cyclic olefin resins into porous materials | MATERIA, INC. | 2003-10-02 | — | — | US | disclosed |
| US-6369181-B1 | COMONOMERS COMPRISING 5-NORBORNENE-2-CARBOXYLIC ACID ESTERS, 5-NORBORNENE-2,3-DICARBOXYLIC ACID MONOMETHYL ESTER, AND MALEIC ANHYDRIDE; ODORLESS; ULTRAVIOLET RAYS OF KRYPTON FLUORIDE OR ARGON FLUORIDE | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2002-04-09 | — | — | US | disclosed |
| EP-1185869-A2 | LIGAND-ANCHOR CONJUGATES FOR PRODUCING A BIOSENSOR LAYER | Graffinity Pharmaceutical Design GmbH (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-6348296-B1 | COPOLYMER CONSISTING OF 2,3-DI-TERT-BUTYL-5-NORBORNENE-2,3-DICARBOXYLATE, ANOTHER NORBORNENE MONOMER, AND MALEIC ANHYDRIDE | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2002-02-19 | — | — | US | disclosed |
| WO-2000073796-A2 | LIGAND-ANCHOR CONJUGATES FOR PRODUCING A BIOSENSOR LAYER | GRAFFINITY PHARMACEUTICAL DESIGN GMBH (DE) | 2000-12-07 | — | — | WO | disclosed |