Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11458105 | 0.90 | DRD3 (0.67) | DRD3OPRM1OPRD1OPRK1LMNA | |
| Hydrochloric Acid SCHEMBL29704406 | 0.88 | DRD3 (0.58) | DRD3OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL19717856 | 0.88 | DRD3 (0.64) | DRD3OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL614226 | 0.87 | OPRM1 (0.71) | DRD3OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL28398971 | 0.86 | OPRM1 (0.65) | DRD3OPRM1OPRD1OPRK1LMNA | |
| Hydrochloric Acid SCHEMBL3321232 | 0.86 | OPRM1 (0.70) | DRD3OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL15734501 | 0.84 | DRD3 (0.70) | DRD3OPRM1OPRD1OPRK1LMNA | |
| Hydrochloric Acid SCHEMBL32659731 | 0.84 | DRD3 (0.51) | DRD3OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL22790441 | 0.82 | OPRM1 (0.60) | DRD3OPRM1OPRD1OPRK1LMNA | |
| Hydrochloric Acid SCHEMBL29427652 | 0.81 | DRD3 (0.68) | DRD3OPRM1OPRD1OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184584-A1 | STABLE PACKAGING SYSTEM FOR MOISTURE AND OXYGEN SENSITIVE PHARMACEUTICAL DOSAGE FORMS | ASCENT PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |