SCHEMBL614226

SCHEMBL614226

CCC(=O)OC1(c2ccccc2)CCN(C)CC1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 6/20 0.71
OPRD1 P41143 4/20 0.71
OPRK1 P41145 4/20 0.71
DRD3 P35462 3/20 0.66
LMNA P02545 1/20 0.61
SLC22A1 O15245 1/20 0.55
SLC6A4 P31645 1/20 0.55
ADRA1A P35348 1/20 0.55
KCNH2 Q12809 1/20 0.55
NPSR1 Q6W5P4 1/20 0.47
DRD2 P14416 1/20 0.47
DRD4 P21917 1/20 0.47
CHRM5 P08912 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
P2RX7 Q99572 1/20 0.42
SCN1A P35498 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3321232 0.99 OPRM1 (0.70) OPRM1OPRD1OPRK1DRD3LMNA
SCHEMBL28398971 0.88 OPRM1 (0.65) OPRM1OPRD1OPRK1DRD3LMNA
SCHEMBL19475378 0.87 DRD3 (0.68) OPRM1OPRD1OPRK1DRD3LMNA
SCHEMBL11458105 0.86 DRD3 (0.67) OPRM1OPRD1OPRK1DRD3LMNA
Hydrochloric Acid SCHEMBL10969957 0.86 OPRM1 (0.54) OPRM1OPRD1OPRK1DRD3LMNA
SCHEMBL19717856 0.83 DRD3 (0.64) OPRM1OPRD1OPRK1DRD3LMNA
SCHEMBL22790441 0.83 OPRM1 (0.60) OPRM1OPRD1OPRK1DRD3LMNA
SCHEMBL15734501 0.83 DRD3 (0.70) OPRM1OPRD1OPRK1DRD3LMNA
SCHEMBL11196518 0.82 OPRM1 (0.54) OPRM1OPRD1OPRK1DRD3LMNA
Hydrochloric Acid SCHEMBL11204271 0.81 OPRM1 (0.53) OPRM1OPRD1OPRK1DRD3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4049985-B1 FILLER FOR WALL COATINGS AMBERGER KAOLINWERKE EDUARD KICK GMBH & CO KG (DE) 2026-04-01 EP claimed
CN-119903917-A Multi-mode-based priori-posterior knowledge prompting and reasoning method 大连大学 2025-04-29 CN claimed
US-20240343784-A1 TREATMENT OF MEDICATION OVERUSE HEADACHE USING ANTI-CGRP OR ANTI-CGRP-R ANTIBODIES H LUNDBECK AS (DK) 2024-10-17 US claimed
US-12118110-B2 Identity query language systems and methods Strata Identity, Inc. (US) 2024-10-15 US claimed
CN-118763735-A Comprehensive energy system multi-time scale optimization scheduling strategy based on economic model predictive control 华北电力大学 2024-10-11 CN claimed
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
US-12065391-B2 Composition containing N-(n-butyl) thiophosphoric triamide adducts and reaction products KOCH AGRONOMIC SERVICES, LLC (US) 2024-08-20 US claimed
EP-4168209-B1 COMPUTER IMPLEMENTED METHOD OF AND OPTIMISATION TOOL FOR REFINEMENT OF LASER CUTTING PROCESS PARAMETERS BY MEANS OF AN OPTIMIZATION TOOL, WITH CORRESPONDING COMPUTER PROGRAM BYSTRONIC LASER AG (CH) 2024-06-05 EP claimed
US-20240083877-A1 NOVEL SCAFFOLD OF ADENYLYL CYCLASE INHIBITORS FOR CHRONIC PAIN AND OPIOID DEPENDENCE PURDUE RESEARCH FOUNDATION (US) 2024-03-14 US claimed
CN-116005453-A Preparation method and application process of natural fiber fabric flame retardant with water washing resistance, no aldehyde, no color change and no pungent odor 深圳市尼森实业有限公司 2023-04-25 CN claimed
WO-2023019186-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER THE JOHNS HOPKINS UNIVERSITY (US) 2023-02-16 WO claimed
WO-2022246104-A1 ELECTROCHEMICAL SENSOR FOR THE MEASUREMENT OF GLUCOSE CONCENTRATION ARKANSAS STATE UNIVERSTIY-JONESBORO (US) 2022-11-24 WO claimed
US-20220318416-A1 IDENTITY QUERY LANGUAGE SYSTEMS AND METHODS WESTERN ALLIANCE BANK 2022-10-06 US claimed
WO-2022212949-A1 IDENTITY QUERY LANGUAGE SYSTEMS AND METHODS Strata Identity, Inc. (US) 2022-10-06 WO claimed
EP-3514183-B1 PELLETIZED POLYMER COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-05-04 EP claimed
WO-2022058113-A1 COMPUTER IMPLEMENTED METHOD OF AND OPTIMISATION TOOL FOR REFINEMENT OF LASER CUTTING PROCESS PARAMETERS BY MEANS OF AN OPTIMIZATION TOOL BYSTRONIC LASER AG (CH) 2022-03-24 WO claimed
EP-3970905-A1 COMPUTER IMPLEMENTED METHOD OF AND OPTIMISATION TOOL FOR REFINEMENT OF LASER CUTTING PROCESS PARAMETERS BY MEANS OF AN OPTIMIZATION TOOL Bystronic Laser AG (CH) 2022-03-23 EP claimed
WO-2014153099-A2 METHOD FOR USING EXHALED BREATH TO DETERMINE THE PRESENCE OF DRUG Pulmonary Analytics (US) 2014-09-25 WO claimed
US-20140288454-A1 Method For Using Exhaled Breath to Determine the Presence of Drug Pulmonary Analytics (US) 2014-09-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240083877-A1 NOVEL SCAFFOLD OF ADENYLYL CYCLASE INHIBITORS FOR CHRONIC PAIN AND OPIOID DEPENDENCE CAP1, ADCY1, ADCYAP1R1 OPRM1 28/4885OPRD1 14/4885OPRK1 11/4885
US-12065391-B2 Composition containing N-(n-butyl) thiophosphoric triamide adducts and reaction products PNP, PFAS, MTAP OPRM1 3976/4885OPRD1 4769/4885OPRK1 4797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.