Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177621 | 0.89 | RARB (0.61) | MAPK1RARBMAPTKMT2ATAS2R14 | |
| SCHEMBL1953300 | 0.83 | MAPK1 (0.65) | MAPK1RARBPKMHSD17B10MAPT | |
| SCHEMBL29096677 | 0.81 | MAPK1 (0.63) | MAPK1RARBPKMHSD17B10MAPT | |
| Dimethylamine SCHEMBL28980764 | 0.79 | MAPK1 (0.64) | MAPK1RARBPKMHSD17B10MAPT | |
| SCHEMBL23066263 | 0.77 | MAPK1 (0.61) | MAPK1PKMHSD17B10MAPTKMT2A | |
| Benzoic Acid 1-(3-Methyl)Butyl Ester SCHEMBL5309105 | 0.77 | LMNA (0.59) | MAPK1RARBPKMHSD17B10MAPT | |
| SCHEMBL6538723 | 0.76 | MAPK1 (1.00) | MAPK1RARBPKMHSD17B10KMT2A | |
| Terephthalic Acid SCHEMBL22719986 | 0.75 | MAPK1 (0.63) | MAPK1RARBPKMHSD17B10MAPT | |
| SCHEMBL1953298 | 0.74 | MAPK1 (0.73) | MAPK1PKMHSD17B10MAPTKMT2A | |
| SCHEMBL20414856 | 0.73 | RARB (0.57) | MAPK1RARBPKMHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017180691-A1 | PET SOLUTIONS AND METHODS OF MAKING PET SOLUTIONS FOR MEDICAL DEVICES | CARDIAC PACEMAKERS, INC. (US) | 2017-10-19 | — | — | WO | disclosed |