Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19508649 | 0.87 | ALDH1A1 (0.46) | HDAC3HDAC1HDAC4HDAC6ALDH1A1 | |
| SCHEMBL11989148 | 0.87 | HDAC3 (0.56) | HDAC3HDAC1HDAC4HDAC6ALDH1A1 | |
| SCHEMBL12589209 | 0.80 | ALDH1A1 (0.50) | HDAC3HDAC1HDAC4HDAC6ALDH1A1 | |
| SCHEMBL1587163 | 0.80 | ALDH1A1 (0.51) | HDAC3HDAC1HDAC4HDAC6ALDH1A1 | |
| SCHEMBL21124416 | 0.80 | KDM4E (0.50) | HDAC1HDAC4HDAC6ALDH1A1HPGD | |
| SCHEMBL14625758 | 0.80 | HDAC3 (0.50) | HDAC3HDAC1HDAC4HDAC6ALDH1A1 | |
| SCHEMBL12265900 | 0.79 | NPC1 (0.55) | HDAC3HDAC1HDAC4HDAC6ALDH1A1 | |
| SCHEMBL25564678 | 0.79 | KMT2A (0.45) | HDAC3HDAC1HDAC4HDAC6ALDH1A1 | |
| SCHEMBL1588287 | 0.79 | NPSR1 (0.51) | HDAC3HDAC1HDAC4HDAC6ALDH1A1 | |
| SCHEMBL14748302 | 0.77 | HDAC3 (0.47) | HDAC3HDAC1HDAC4HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170296566-A9 | METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING MUCOSITIS | GLYCOMIMETICS, INC. (US) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170296566-A9 | METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING MUCOSITIS | SELE, SELP, SELPLG | HDAC3 1371/4885HDAC1 1007/4885HDAC4 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.