Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.44 |
| ▸ | ALPL | P05186 | 5/20 | 0.44 |
| ▸ | XIAP | P98170 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675171 | 0.78 | TSHR (0.48) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL28946984 | 0.78 | TSHR (0.48) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL28981274 | 0.78 | TSHR (0.48) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4436614 | 0.77 | TSHR (0.47) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL29087084 | 0.77 | TSHR (0.47) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4436617 | 0.74 | TSHR (0.44) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL22622062 | 0.73 | TSHR (0.52) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL6454758 | 0.71 | TSHR (0.50) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL15459000 | 0.71 | TSHR (0.50) | TSHRALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL21619453 | 0.70 | TSHR (0.45) | TSHRALDH1A1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298026-A1 | ALL PURPOSE RAFT AGENT | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298026-A1 | ALL PURPOSE RAFT AGENT | NPC1L1, RFTN1, SGMS2 | TSHR 4058/4885ALDH1A1 817/4885MEN1 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.