Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 19/20 | 0.63 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661871 | 1.00 | SELE (0.63) | SELESELL | |
| SCHEMBL17881674 | 1.00 | SELE (0.63) | SELESELL | |
| SCHEMBL19479262 | 1.00 | SELE (0.63) | SELESELL | |
| SCHEMBL16661873 | 1.00 | SELE (0.63) | SELESELL | |
| SCHEMBL19479263 | 1.00 | SELE (0.63) | SELESELL | |
| SCHEMBL19943724 | 1.00 | SELE (0.63) | SELESELL | |
| SCHEMBL19943722 | 1.00 | SELE (0.63) | SELESELL | |
| SCHEMBL16659821 | 1.00 | SELE (0.63) | SELESELL | |
| SCHEMBL22006643 | 1.00 | SELE (0.63) | SELESELL | |
| SCHEMBL19939770 | 0.95 | SELE (0.65) | SELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332491-B2 | E-selectin antagonist compounds, compositions, and methods of use | GLYCOMIMETICS, INC. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210017215-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2021-01-21 | — | — | US | disclosed |
| US-10766916-B2 | E-selectin antagonist compounds, compositions, and methods of use | GLYCOMIMETICS, INC. (US) | 2020-09-08 | — | — | US | disclosed |
| EP-2794626-B3 | E-SELECTIN ANTAGONIST COMPOUNDS | GLYCOMIMETICS INC (US) | 2020-08-05 | — | — | EP | disclosed |
| US-20200157134-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2020-05-21 | — | — | US | disclosed |
| US-20180066006-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2018-03-08 | — | — | US | disclosed |
| US-9867841-B2 | Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells | GLYCOMIMETICS, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| EP-2794626-B1 | E-SELECTIN ANTAGONIST COMPOUNDS | GLYCOMIMETICS INC (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9796745-B2 | E-selectin antagonist compounds, compositions, and methods of use | GLYCOMIMETICS, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170296566-A9 | METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING MUCOSITIS | GLYCOMIMETICS, INC. (US) | 2017-10-19 | — | — | US | disclosed |
| US-20150329543-A1 | PRODRUGS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332491-B2 | E-selectin antagonist compounds, compositions, and methods of use | SELE, SELPLG, SELP | SELE 1/4885SELL 4/4885 |
| US-20210017215-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SELE, SELPLG, SELP | SELE 1/4885SELL 4/4885 |
| US-10766916-B2 | E-selectin antagonist compounds, compositions, and methods of use | SELE, SELPLG, SELP | SELE 1/4885SELL 4/4885 |
| US-20180066006-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SELE, SELPLG, SELP | SELE 1/4885SELL 4/4885 |
| US-20170296566-A9 | METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING MUCOSITIS | SELE, SELP, SELPLG | SELE 1/4885SELL 4/4885 |
| US-20150329543-A1 | PRODRUGS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | ITPA, IMPDH2, IDO1 | SELE 3719/4885SELL 2877/4885 |
| US-20200157134-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SELE, SELPLG, SELP | SELE 1/4885SELL 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.