Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.48 |
| ▸ | CDC25B | P30305 | 8/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | FGF1 | P05230 | 2/20 | 0.41 |
| ▸ | FGF2 | P09038 | 2/20 | 0.41 |
| ▸ | VEGFA | P15692 | 2/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990249 | 0.92 | PTPN1 (0.48) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL22750896 | 0.92 | PTPN1 (0.48) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL38652098 | 0.88 | PTPN1 (0.49) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL30052037 | 0.84 | NT5E (0.53) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL29410626 | 0.82 | PTPN1 (0.43) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL6552379 | 0.80 | PTPN1 (0.50) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL14409790 | 0.80 | NT5E (0.51) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL25084213 | 0.79 | LMNA (0.58) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL13527782 | 0.79 | LMNA (0.58) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL17701112 | 0.79 | LMNA (0.58) | PTPN1CDC25BPTPN2PTPN11PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3231804-B1 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | MASSACHUSETTS GEN HOSPITAL (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3231804-A1 | COMPOUNDS AND COMPOSITIONS FOR THE DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE AND RELATED DISORDERS | The General Hospital Corporation (US) | 2017-10-18 | — | — | EP | disclosed |