Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.46 |
| ▸ | CDC25B | P30305 | 8/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FGF1 | P05230 | 2/20 | 0.42 |
| ▸ | FGF2 | P09038 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 2/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552379 | 0.94 | PTPN1 (0.50) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL472853 | 0.90 | NT5E (0.44) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL6552374 | 0.88 | TACR2 (0.43) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL14075622 | 0.86 | LGALS8 (0.48) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL14409788 | 0.86 | LGALS8 (0.48) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL2629592 | 0.86 | LGALS8 (0.48) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL6553266 | 0.84 | SSTR1 (0.44) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6553262 | 0.84 | SSTR1 (0.44) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6553224 | 0.83 | SSTR1 (0.50) | NT5EPTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL472852 | 0.83 | LGALS8 (0.42) | NT5EPTPN1CDC25BSSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637578-B2 | Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins | ISIS INNOVATION LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |
| US-20070213506-A1 | Reagents And Methods For The Formation Of Disulfide Bonds And The Glycosylation Of Proteins | ISIS INNOVATION LIMITED (GB) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213506-A1 | Reagents And Methods For The Formation Of Disulfide Bonds And The Glycosylation Of Proteins | SCLY, PTMS, TST | NT5E 3172/4885PTPN1 1465/4885CDC25B 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.