Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672011 | 0.79 | HCRTR1 (0.45) | KDM4EALDH1A1PKMHCRTR1HCRTR2 | |
| SCHEMBL1586099 | 0.78 | HCRTR1 (0.53) | KDM4EALDH1A1LMNASMN1; SMN2HCRTR1 | |
| SCHEMBL30611553 | 0.78 | HCRTR1 (0.53) | KDM4EALDH1A1LMNASMN1; SMN2HCRTR1 | |
| SCHEMBL16040262 | 0.77 | HCRTR1 (0.53) | KDM4EALDH1A1LMNAHCRTR1HCRTR2 | |
| SCHEMBL20551259 | 0.77 | HCRTR1 (0.52) | KDM4EALDH1A1LMNASMN1; SMN2HCRTR1 | |
| SCHEMBL16039749 | 0.77 | HCRTR1 (0.52) | KDM4EALDH1A1LMNASMN1; SMN2HCRTR1 | |
| SCHEMBL13737118 | 0.76 | HCRTR1 (0.52) | KDM4EALDH1A1HCRTR1HCRTR2L3MBTL1 | |
| SCHEMBL19472425 | 0.76 | KDM4E (0.43) | KDM4EASPHKDM8HCRTR1HCRTR2 | |
| SCHEMBL30361654 | 0.76 | ALDH1A1 (0.39) | KDM4EALDH1A1LMNASMN1; SMN2ASPH | |
| SCHEMBL29424961 | 0.76 | GABRP (0.39) | KDM4EALDH1A1LMNAMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442965-B1 | NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2021-05-26 | — | — | EP | disclosed |
| WO-2017178344-A1 | NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |