Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 4/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.61 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 2/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.61 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.61 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.61 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933245 | 1.00 | CXCL8 (0.65) | CXCL8AKR1B1CTBP2TTRPTGS2 | |
| SCHEMBL27930873 | 0.98 | CXCL8 (0.62) | CXCL8AKR1B1CTBP2TTRPTGS2 | |
| SCHEMBL11226769 | 0.98 | CXCL8 (0.62) | CXCL8AKR1B1CTBP2TTRPTGS2 | |
| Ammonia Solution, Strong SCHEMBL28173002 | 0.98 | CXCL8 (0.62) | CXCL8AKR1B1CTBP2TTRPTGS2 | |
| Bromide SCHEMBL8119525 | 0.98 | CXCL8 (0.62) | CXCL8AKR1B1CTBP2TTRPTGS2 | |
| Hydrochloric Acid SCHEMBL2529217 | 0.98 | CXCL8 (0.62) | CXCL8AKR1B1CTBP2TTRPTGS2 | |
| Acetic Acid SCHEMBL11770944 | 0.94 | CXCL8 (0.59) | CXCL8AKR1B1CTBP2TTRPTGS2 | |
| SCHEMBL11776630 | 0.92 | CXCL8 (0.57) | CXCL8AKR1B1CTBP2TTRPTGS2 | |
| SCHEMBL2547244 | 0.84 | AKR1B1 (0.63) | CXCL8AKR1B1TTRPTGS2AKR1B10 | |
| SCHEMBL31365969 | 0.84 | CTBP2 (0.58) | CXCL8CTBP2RAB9APKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1977 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| US-20250034297-A1 | VANADIUM-BASED CATALYTIC SYSTEM INCLUDING ACTIVATOR AND METHOD FOR OLEFIN POLYMERIZATION | CHANGCHUN UNIVERSITY OF TECHNOLOGY (CN) | 2025-01-30 | — | — | US | claimed |
| WO-2024176515-A1 | SUBSTRATE PROCESSING METHOD, SUBSTRATE PROCESSING APPARATUS, AND PROCESSING LIQUID | 株式会社ＳＣＲＥＥＮホールディングス | 2024-08-29 | — | — | WO | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-114199802-B | Method for identifying vegetable dye in dyed textile | 中国纺织信息中心 | 2023-12-22 | — | — | CN | claimed |
| US-20230312474-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-10-05 | — | — | US | claimed |
| WO-2023137518-A1 | PLATINUM COMPLEXES | Western Sydney University (AU) | 2023-07-27 | — | — | WO | claimed |
| CN-116396156-A | Preparation method of o-hydroxyphenylacetic acid | 苏利(宁夏)新材料科技有限公司 | 2023-07-07 | — | — | CN | claimed |
| EP-4206184-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-05 | — | — | EP | claimed |
| CN-115124440-A | Preparation method of prothioconazole intermediate | 江苏七洲绿色科技研究院有限公司 | 2022-09-30 | — | — | CN | claimed |
| US-5221772-A | Heating o-chlorophenyl/acetic acid with alkali metal hydroxide in organic solvent in presence of copper salt | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-22 | — | — | US | claimed |
| US-5189170-A | Process for the preparation of phenylacetic derivatives of thieno-pyridines | SANOFI (FR) | 1993-02-23 | — | — | US | claimed |
| US-4740510-A | Derivatives of alpha-(2-oxo 2,4,5,6,7,7a-hexahydro thieno[3,2-c]5-pyridyl) phenyl acetic acid, and their use as platelet and thrombotic aggregation inhibitors | SANOFI (S.A.) (FR) | 1988-04-26 | — | — | US | claimed |
| EP-0099802-B1 | THIENO(3,2-C) PYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | ELF SANOFI (FR) | 1987-02-04 | — | — | EP | claimed |
| EP-0057047-B1 | PROCESS FOR THE PREPARATION OF 2-(2,4-DICHLOROPHENOXY) PHENYLACETIC ACID | RECKITT AND COLMAN PRODUCTS LIMITED (GB) | 1984-08-08 | — | — | EP | claimed |
| US-4410724-A | Process for production of o-(2,6-dichloroanilino)-phenylacetic acid | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-18 | — | — | US | claimed |
| US-4404396-A | Process for the preparation of 2-(2,4-dichlorophenoxy)-phenylacetic acid | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1983-09-13 | — | — | US | claimed |
| US-4390723-A | BIS(8-QUINOLINOLATE) COPPER COMPLEX CATALYST | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1983-06-28 | — | — | US | claimed |
| EP-0057047-A1 | Process for the preparation of 2-(2,4-dichlorophenoxy) phenylacetic acid | RECKITT AND COLMAN PRODUCTS LIMITED (GB) | 1982-08-04 | — | — | EP | claimed |
| US-4084061-A | REARRANGEMENT OF TOLYL OR CHLOROTOLYL SODIUM, CARBOXYLATION | IHARA CHEMICAL INDUSTRY CO., LTD. (JA) | 1978-04-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312474-A1 | PHENOL DERIVATIVE | TYR, NCOR1, BET1 | CXCL8 3036/4885AKR1B1 1515/4885CTBP2 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.