Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.63 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.59 |
| ▸ | TTR | P02766 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.59 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.59 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798814 | 0.91 | AKR1B1 (0.58) | AKR1B1CXCL8TTRPTGS2AKR1B10 | |
| SCHEMBL9890643 | 0.85 | CXCL8 (0.54) | AKR1B1CXCL8TTRPTGS2AKR1B10 | |
| SCHEMBL6194277 | 0.84 | PNMT (0.58) | AKR1B1CXCL8TTRPTGS2AKR1B10 | |
| SCHEMBL194831 | 0.84 | CXCL8 (0.65) | AKR1B1CXCL8TTRPTGS2AKR1B10 | |
| SCHEMBL29933245 | 0.84 | CXCL8 (0.65) | AKR1B1CXCL8TTRPTGS2AKR1B10 | |
| SCHEMBL11691926 | 0.83 | AKR1B1 (0.77) | AKR1B1CXCL8TTRPTGS2AKR1B10 | |
| SCHEMBL71912 | 0.83 | AKR1B1 (0.59) | AKR1B1CXCL8TTRPTGS2AKR1B10 | |
| SCHEMBL11078314 | 0.83 | AKR1B1 (0.67) | AKR1B1CXCL8TTRPTGS2AKR1B10 | |
| SCHEMBL6961042 | 0.83 | PNMT (0.56) | AKR1B1CXCL8TTRPTGS2AKR1B10 | |
| SCHEMBL11226769 | 0.83 | CXCL8 (0.62) | AKR1B1CXCL8TTRPTGS2AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4685176-A1 | 2-COMPONENT FOAMS BASED ON ACETYLACETONATE AND AMINES | Henkel AG & Co. KGaA (DE) | 2026-01-28 | — | — | EP | claimed |
| US-12528974-B2 | Polishing slurry composition | KCTECH CO., LTD. (KR) | 2026-01-20 | — | — | US | claimed |
| CN-114994196-B | High performance liquid chromatography separation method for guanfacine hydrochloride intermediate 2, 6-dichlorophenylacetic acid and impurities | 上海应用技术大学 | 2024-12-31 | — | — | CN | claimed |
| US-20240158667-A1 | POLISHING SLURRY COMPOSITION | KCTECH CO., LTD. (KR) | 2024-05-16 | — | — | US | claimed |
| WO-2022231115-A1 | POLISHING SLURRY COMPOSITION | 주식회사 케이씨텍 | 2022-11-03 | — | — | WO | claimed |
| CN-114478122-A | Novel functional fertilizer synergist and application | 郑州郑氏化工产品有限公司 | 2022-05-13 | — | — | CN | claimed |
| EP-1332167-B1 | PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE | GEN ELECTRIC (US) | 2008-09-17 | — | — | EP | claimed |
| EP-1018525-B1 | Process for preparing polyurethane foam | GEN ELECTRIC (US) | 2006-08-30 | — | — | EP | claimed |
| EP-1362073-B1 | PROCESS TO ENHANCE POLYURETHANE FOAM PERFORMANCE | GEN ELECTRIC (US) | 2005-12-14 | — | — | EP | claimed |
| EP-1534766-A1 | PROCESS FOR PREPARING POLYURETHANE FOAM | GENERAL ELECTRIC COMPANY (US) | 2005-06-01 | — | — | EP | claimed |
| WO-2002048229-A2 | PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE | CROMPTON CORPORATION (US) | 2002-06-20 | — | — | WO | claimed |
| US-6395796-B1 | CONDENSATION OF POLYISOCYANATE AND POLYOL USING DELAYED ACTION AMINE CATALYST FORMED BY REACTION OF HALOCARBOXYLIC ACID AND TERTIARY AMINE | CROMPTON CORPORATION | 2002-05-28 | — | — | US | claimed |
| US-6387972-B1 | MIXTURE CONTAINING TERTIARY AMINE ADJUVANT | CROMPTON CORPORATION | 2002-05-14 | — | — | US | claimed |
| EP-0710648-B1 | Method for producing oxyindoles | KI CHEMICAL INDUSTRY CO LTD (JP) | 2002-04-03 | — | — | EP | claimed |
| CN-1269372-A | Process for producing polyurethane foam plastics | CK THE WHITAKER CORP (US) | 2000-10-11 | — | — | CN | claimed |
| EP-1018525-A1 | Process for preparing polyurethane foam | CK WITCO CORPORATION (US) | 2000-07-12 | — | — | EP | claimed |
| US-5679799-A | Method for producing oxyindoles | K-I CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| EP-0710648-A1 | Method for producing oxyindoles | K I CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-08 | — | — | EP | claimed |
| US-4486576-A | NICKEL-CATALYZED COUPLING | UNION CARBIDE CORPORATION (US) | 1984-12-04 | — | — | US | claimed |
| EP-0095042-A1 | Aromatic coating materials from aryl polyhalides | UNION CARBIDE CORPORATION (US) | 1983-11-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528974-B2 | Polishing slurry composition | ACP1, CA1, CA11 | AKR1B1 2688/4885CXCL8 4755/4885TTR 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.