Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
| ▸ | RHEB | Q15382 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19484248 | 0.87 | SMN1; SMN2 (0.33) | SMN1; SMN2LMNAMAPTHTTPOLB | |
| SCHEMBL18796108 | 0.86 | LMNA (0.32) | SMN1; SMN2LMNAMAPTHTTPOLB | |
| SCHEMBL19484252 | 0.85 | AR (0.33) | SMN1; SMN2LMNAMAPTHTTPOLB | |
| SCHEMBL18796118 | 0.80 | LMNA (0.39) | SMN1; SMN2LMNAMAPTHTTPOLB | |
| SCHEMBL19472018 | 0.79 | MAPT (0.35) | SMN1; SMN2LMNAMAPTHTTPOLB | |
| SCHEMBL20551083 | 0.79 | LMNA (0.36) | SMN1; SMN2LMNAMAPTHTTPOLB | |
| SCHEMBL19484251 | 0.78 | LMNA (0.35) | SMN1; SMN2LMNAMAPTHTTPOLB | |
| SCHEMBL18796243 | 0.78 | — | — | |
| SCHEMBL12488150 | 0.77 | ALDH1A1 (0.33) | SMN1; SMN2LMNAMAPTHTTPOLB | |
| SCHEMBL29355058 | 0.77 | ALDH1A1 (0.33) | SMN1; SMN2LMNAMAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178408-A1 | MICROBIOCIDAL SILICON CONTAINING ARYL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-19 | — | — | WO | disclosed |