Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19480970 | 1.00 | ACACB (0.37) | ACACBMAPK1L3MBTL1MAPTMEN1 | |
| SCHEMBL19484457 | 0.81 | KDM4E (0.42) | ACACBMAPTGABRA5SIGMAR1ALDH1A1 | |
| SCHEMBL19484456 | 0.81 | KDM4E (0.42) | ACACBMAPTGABRA5SIGMAR1ALDH1A1 | |
| SCHEMBL2608835 | 0.80 | GABRA5 (0.42) | MAPK1L3MBTL1MEN1KMT2AGABRA5 | |
| SCHEMBL19479367 | 0.78 | HPGD (0.47) | ACACBMAPK1L3MBTL1MAPTKMT2A | |
| SCHEMBL19484455 | 0.78 | HPGD (0.47) | ACACBMAPK1L3MBTL1MAPTKMT2A | |
| SCHEMBL20911728 | 0.77 | MEN1 (0.44) | ACACBMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL19484272 | 0.76 | ACACB (0.40) | ACACBL3MBTL1ALDH1A1 | |
| SCHEMBL19484271 | 0.76 | ACACB (0.40) | ACACBL3MBTL1ALDH1A1 | |
| SCHEMBL2006083 | 0.74 | MAPT (0.52) | MAPTGABRA5ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442958-B1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2020-05-06 | — | — | EP | disclosed |
| WO-2017178340-A1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |