Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | ITGAL | P20701 | 2/20 | 0.35 |
| ▸ | TRHR | P34981 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 2/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27363572 | 0.77 | CYP3A4 (0.56) | CYP3A4SLC7A5NLNHRH3ALDH1A1 | |
| SCHEMBL18804718 | 0.77 | ITGB2 (0.44) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL19730312 | 0.72 | BRD4 (0.33) | — | |
| SCHEMBL19730313 | 0.69 | — | — | |
| SCHEMBL19730315 | 0.69 | — | — | |
| SCHEMBL18804729 | 0.68 | SLC6A5 (0.42) | SLC6A5HRH3 | |
| SCHEMBL27414269 | 0.66 | CYP3A4 (0.46) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL28624947 | 0.65 | TRHR (0.43) | HIF1ACYP3A4SLC7A5ITGB2ICAM1 | |
| SCHEMBL5808674 | 0.64 | HTR1D (0.51) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL10795770 | 0.64 | ITGB2 (0.46) | CYP3A4SLC7A5ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795566-B2 | Imidazole compound and liposome containing same | FUJIFILM CORPORATION (JP) | 2017-10-24 | — | — | US | disclosed |