SCHEMBL19485306

SCHEMBL19485306

c1ccc(N(c2ccccc2)c2ccc(-c3cc(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)c4[nH]c5ccccc5c4c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HTR2B P41595 2/20 0.39
HTR5A P47898 2/20 0.39
TDO2 P48775 2/20 0.39
KIF11 P52732 4/20 0.38
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
MMP8 P22894 2/20 0.38
MMP13 P45452 2/20 0.38
AHR P35869 2/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10003892 1.00 HPGD (0.40) HPGDMAPK1HTTSMN1; SMN2HTR2B
SCHEMBL18905175 0.99 HPGD (0.42) HPGDMAPK1HTTSMN1; SMN2HTR2B
SCHEMBL19485311 0.97 HPGD (0.43) HPGDMAPK1HTTSMN1; SMN2HTR2B
SCHEMBL19485308 0.91 HTR2B (0.45) HPGDMAPK1HTTSMN1; SMN2HTR2B
SCHEMBL19485305 0.90 HPGD (0.41) HPGDMAPK1HTTSMN1; SMN2HTR2B
SCHEMBL19485320 0.88 KDM4E (0.37) HPGDMAPK1HTTSMN1; SMN2HTR2B
SCHEMBL17177848 0.88 HPGD (0.50) HPGDMAPK1HTTSMN1; SMN2HTR2B
SCHEMBL7048827 0.88 HPGD (0.50) HPGDMAPK1HTTSMN1; SMN2HTR2B
SCHEMBL19485307 0.88 KIF11 (0.40) HPGDMAPK1HTTSMN1; SMN2HTR2B
SCHEMBL18310312 0.87 KIF11 (0.45) HTR2BHTR5ATDO2KIF11BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10319922-B2 Compound for organic electronic element, organic electronic element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2019-06-11 US disclosed
US-10319923-B2 Compound for organic electronic element, organic electronic element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2019-06-11 US disclosed
US-20170301868-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-10-19 US disclosed
US-20170301868-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170301868-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, GPX1 HPGD 3050/4885MAPK1 198/4885HTT 4477/4885
US-10319922-B2 Compound for organic electronic element, organic electronic element comprising the same and electronic device thereof PIEZO1, GPX1, OCIAD1 HPGD 3156/4885MAPK1 214/4885HTT 4157/4885
US-10319923-B2 Compound for organic electronic element, organic electronic element comprising the same and electronic device thereof PIEZO1, GPX1, OCIAD1 HPGD 3156/4885MAPK1 214/4885HTT 4157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.