Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.45 |
| ▸ | HTR3B | O95264 | 3/20 | 0.45 |
| ▸ | HTR3A | P46098 | 3/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968961 | 0.82 | ADRB1 (0.49) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL17834368 | 0.82 | ADRB1 (0.49) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10445779 | 0.80 | KDM4E (0.46) | ADRB1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9247465 | 0.79 | KDM4E (0.48) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9249560 | 0.78 | GBA1 (0.54) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20708875 | 0.78 | GBA1 (0.54) | GBA1SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL27569317 | 0.77 | GBA1 (0.53) | GBA1SLC6A2SLC6A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9251137 | 0.77 | GBA1 (0.53) | GBA1SLC6A2SLC6A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9253771 | 0.77 | GBA1 (0.53) | GBA1SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL300437 | 0.77 | ADRB1 (0.62) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |