Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9247465 | 0.99 | KDM4E (0.48) | KDM4EALDH1A1MAPTTACR3GFER | |
| SCHEMBL19485484 | 0.80 | ADRB1 (0.49) | MEN1KMT2AADRB1 | |
| SCHEMBL9257637 | 0.78 | HSD11B1 (0.51) | ALDH1A1MAPTGFERCASP6MEN1 | |
| SCHEMBL9255556 | 0.78 | SLC6A4 (0.64) | TACR3GAALMNA | |
| SCHEMBL14559864 | 0.77 | MEN1 (0.56) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3040782 | 0.77 | KCNH2 (0.51) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3026559 | 0.76 | CYP2C9 (0.67) | ALDH1A1TACR3GAAMEN1KMT2A | |
| SCHEMBL4775580 | 0.74 | CCR5 (0.54) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4775057 | 0.74 | SMN1; SMN2 (0.63) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27588068 | 0.74 | CYP2C9 (0.47) | ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378207-A1 | Cyclic amine compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-18 | — | — | EP | disclosed |