Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305994 | 0.89 | HRH2 (0.48) | HRH2HRH1 | |
| SCHEMBL16294766 | 0.89 | HRH2 (0.48) | HRH2HRH1 | |
| SCHEMBL16295733 | 0.83 | HRH2 (0.46) | HRH2HRH1ACEMCL1ITGB1 | |
| SCHEMBL16295734 | 0.83 | HRH2 (0.46) | HRH2HRH1ACEMCL1ITGB1 | |
| SCHEMBL17994262 | 0.83 | HRH2 (0.44) | HRH2HRH1S1PR1S1PR3S1PR5 | |
| SCHEMBL16295824 | 0.82 | ITGB3 (0.49) | HRH2HRH1ITGB1ITGA4 | |
| SCHEMBL16295823 | 0.82 | ITGB3 (0.49) | HRH2HRH1ITGB1ITGA4 | |
| SCHEMBL16343092 | 0.80 | ITGB3 (0.50) | HRH2HRH1S1PR1S1PR3S1PR5 | |
| SCHEMBL16295738 | 0.80 | ITGB3 (0.50) | HRH2HRH1S1PR1S1PR3S1PR5 | |
| SCHEMBL22384134 | 0.80 | HRH2 (0.44) | HRH2HRH1ITGB1ITGA4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |