Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834454 | 1.00 | CYP3A4 (0.37) | CYP3A4CYP2C9APPS1PR1S1PR4 | |
| SCHEMBL17834458 | 0.99 | CYP3A4 (0.36) | CYP3A4CYP2C9APPS1PR1S1PR4 | |
| SCHEMBL17834420 | 0.97 | PYGL (0.33) | CYP3A4CYP2C9APPS1PR1S1PR4 | |
| SCHEMBL22384469 | 0.94 | CYP3A4 (0.36) | CYP3A4CYP2C9APPS1PR1S1PR4 | |
| SCHEMBL22384480 | 0.93 | CYP3A4 (0.34) | CYP3A4CYP2C9APPS1PR1S1PR4 | |
| SCHEMBL17834771 | 0.93 | S1PR1 (0.39) | S1PR1S1PR4S1PR5S1PR3F2 | |
| SCHEMBL17995211 | 0.92 | DPP4 (0.37) | S1PR1S1PR3F10ST14KDM1A | |
| SCHEMBL17834633 | 0.91 | F2 (0.35) | S1PR1S1PR5F2F10PLG | |
| SCHEMBL17834419 | 0.91 | S1PR1 (0.35) | S1PR1S1PR5S1PR3F10ST14 | |
| SCHEMBL17834639 | 0.91 | S1PR1 (0.38) | S1PR1S1PR4S1PR5S1PR3PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10034886-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2018-07-31 | — | — | US | disclosed |
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10034886-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | CYP3A4 3252/4885CYP2C9 2291/4885APP 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.