Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515247 | 0.99 | MMP2 (0.47) | MMP2KLKB1TSHRHDAC1CALCRL | |
| SCHEMBL19445843 | 0.95 | MMP2 (0.46) | MMP2KLKB1TSHRHDAC1CALCRL | |
| SCHEMBL12515471 | 0.95 | MMP2 (0.46) | MMP2KLKB1TSHRHDAC1CALCRL | |
| SCHEMBL21371587 | 0.93 | KLKB1 (0.41) | MMP2KLKB1TSHRHDAC1CALCRL | |
| SCHEMBL21372002 | 0.93 | MMP2 (0.45) | MMP2KLKB1TSHRHDAC1PTGDR2 | |
| SCHEMBL12518621 | 0.92 | KLKB1 (0.41) | MMP2KLKB1TSHRHDAC1CALCRL | |
| SCHEMBL12518396 | 0.92 | MMP2 (0.46) | MMP2KLKB1TSHRHDAC1PTGDR2 | |
| SCHEMBL19944937 | 0.91 | MMP2 (0.48) | MMP2 | |
| SCHEMBL19486009 | 0.91 | MMP2 (0.44) | MMP2TSHR | |
| SCHEMBL19445788 | 0.90 | MMP2 (0.47) | MMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795575-B2 | Compounds for use in treatment of mucositis | INNOVATION PHARMACEUTICALS INC. (US) | 2017-10-24 | — | — | US | disclosed |