Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.39 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19945230 | 1.00 | TSHR (0.44) | TSHRMMP2LMNAMEN1KMT2A | |
| SCHEMBL12515488 | 0.99 | TSHR (0.45) | TSHRMMP2LMNAMEN1KMT2A | |
| SCHEMBL21371960 | 0.92 | HDAC1 (0.48) | TSHRMMP2HDAC1HDAC3HDAC4 | |
| SCHEMBL19219853 | 0.92 | HDAC1 (0.48) | TSHRMMP2HDAC1HDAC3HDAC4 | |
| SCHEMBL12515244 | 0.91 | HDAC1 (0.47) | TSHRMMP2LMNAMEN1KMT2A | |
| SCHEMBL21372002 | 0.91 | MMP2 (0.45) | TSHRMMP2LMNAMEN1KMT2A | |
| SCHEMBL19445793 | 0.91 | HDAC1 (0.47) | TSHRMMP2LMNAMEN1KMT2A | |
| SCHEMBL12518396 | 0.90 | MMP2 (0.46) | TSHRMMP2LMNAMEN1KMT2A | |
| SCHEMBL21372024 | 0.90 | TSHR (0.47) | TSHRLMNAMEN1KMT2AHDAC1 | |
| SCHEMBL19445643 | 0.89 | ALDH1A1 (0.43) | TSHRMMP2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795575-B2 | Compounds for use in treatment of mucositis | INNOVATION PHARMACEUTICALS INC. (US) | 2017-10-24 | — | — | US | disclosed |