Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003229 | 0.82 | RECQL (0.55) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL14003231 | 0.82 | RECQL (0.55) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL8467373 | 0.78 | KDM4E (0.72) | ALDH1A1KDM4EESR1ESR2PTGS2 | |
| SCHEMBL17371339 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4EESR1ESR2MEN1 | |
| SCHEMBL2026122 | 0.75 | ALDH1A1 (1.00) | ALDH1A1KDM4EESR1ESR2MEN1 | |
| SCHEMBL15272117 | 0.75 | ALDH1A1 (0.69) | ALDH1A1KDM4EESR1ESR2MEN1 | |
| SCHEMBL15272115 | 0.75 | ALDH1A1 (0.69) | ALDH1A1KDM4EESR1ESR2MEN1 | |
| SCHEMBL10739476 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EESR1ESR2MEN1 | |
| SCHEMBL10739481 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EESR1ESR2MEN1 | |
| Dimethylamine SCHEMBL5607765 | 0.73 | AKR1C3 (0.62) | ALDH1A1KDM4EESR1ESR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298097-A1 | Peptide Derivatives and Uses Thereof | NOSOPHARM (FR) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298097-A1 | Peptide Derivatives and Uses Thereof | VIP, IAPP, NGLY1 | ALDH1A1 4866/4885KDM4E 4532/4885ESR1 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.