Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003229 | 1.00 | RECQL (0.55) | RECQLAKR1C3ALDH1A1TSHRMAPT | |
| SCHEMBL1070872 | 0.86 | AKR1C3 (0.55) | RECQLAKR1C3ALDH1A1TSHRMAPT | |
| SCHEMBL13879068 | 0.86 | AKR1C3 (0.55) | RECQLAKR1C3ALDH1A1TSHRMAPT | |
| SCHEMBL21091997 | 0.84 | ALDH1A1 (0.48) | RECQLAKR1C3ALDH1A1TSHRMAPT | |
| SCHEMBL12561790 | 0.82 | RECQL (0.53) | RECQLAKR1C3ALDH1A1TSHRMAPT | |
| SCHEMBL20610671 | 0.82 | MCL1 (0.49) | RECQLAKR1C3ALDH1A1TSHRMAPT | |
| SCHEMBL19487256 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRMAPTGLATDP1 | |
| SCHEMBL27542414 | 0.79 | ALDH1A1 (0.42) | RECQLAKR1C3ALDH1A1TSHRMAPT | |
| SCHEMBL976605 | 0.76 | AKR1C3 (0.64) | RECQLAKR1C3ALDH1A1TSHRMAPT | |
| SCHEMBL976606 | 0.76 | AKR1C3 (0.64) | RECQLAKR1C3ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449544-B2 | p21 peptides | CYCLACEL LIMITED (GB) | 2008-11-11 | — | — | US | disclosed |