Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.48 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808177 | 0.86 | HTT (0.59) | TEAD1YAP1TEAD4TEAD2ALDH1A1 | |
| SCHEMBL19462316 | 0.86 | TRPV1 (0.55) | ALDH1A1MAPTKDM4EPOLBHSD17B10 | |
| SCHEMBL19462148 | 0.84 | TRPV1 (0.63) | ALDH1A1MAPTKDM4EPOLBHSD17B10 | |
| SCHEMBL19462322 | 0.84 | TRPV1 (0.63) | ALDH1A1MAPTKDM4EPOLBHSD17B10 | |
| SCHEMBL19462169 | 0.79 | HTT (0.57) | ALDH1A1HTTMAPTGAAHSD17B10 | |
| SCHEMBL8387458 | 0.79 | CNR2 (0.54) | ALDH1A1HTTMAPTHSD17B10TRPV1 | |
| SCHEMBL19487122 | 0.79 | STAT3 (0.51) | TEAD1YAP1TEAD4TEAD2ALDH1A1 | |
| SCHEMBL14241835 | 0.78 | TEAD1 (0.77) | TEAD1YAP1TEAD4TEAD2ALDH1A1 | |
| SCHEMBL19461988 | 0.78 | APP (0.41) | TEAD1YAP1TEAD4TEAD2ALDH1A1 | |
| SCHEMBL9808286 | 0.78 | HTT (0.56) | TEAD1YAP1TEAD4TEAD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017180769-A1 | SMALL MOLECULES FOR IMMUNOGENIC TREATMENT OF CANCER | CAPTEN THERAPEUTICS INC. (US) | 2017-10-19 | — | — | WO | disclosed |
| US-20150328207-A1 | BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 | AUSPEX PHARMACEUTICALS, INC. | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328207-A1 | BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 | SLC18A2, SLC6A2, SLC18A1 | TEAD1 1560/4885YAP1 3445/4885TEAD4 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.