SCHEMBL19487356

SCHEMBL19487356

CN[C@@H](CCNC(N)=O)C(=O)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 3/20 0.32
RNPEP Q9H4A4 2/20 0.32
DNPEP Q9ULA0 2/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24172621 0.89 C3AR1 (0.36)
SCHEMBL26466762 0.86 ANPEP (0.30) ANPEPRNPEPDNPEP
SCHEMBL19487357 0.81 KISS1R (0.31) ANPEPRNPEPDNPEP
SCHEMBL22536882 0.80 GABRR1 (0.41)
SCHEMBL15478602 0.77 DPP4 (0.39)
SCHEMBL20130643 0.77 DPP4 (0.39)
SCHEMBL15478607 0.76 NPY4R (0.36)
SCHEMBL14632143 0.76 NPY4R (0.36)
SCHEMBL24420295 0.76 C3AR1 (0.35)
SCHEMBL13769032 0.76 NPY4R (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10626144-B2 Peptide derivatives and uses thereof NOSOPHARM (FR) 2020-04-21 US disclosed
US-20170298097-A1 Peptide Derivatives and Uses Thereof NOSOPHARM (FR) 2017-10-19 US disclosed
US-20150328207-A1 BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 AUSPEX PHARMACEUTICALS, INC. 2015-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626144-B2 Peptide derivatives and uses thereof VIP, IAPP, NGLY1 ANPEP 12/4885RNPEP 58/4885DNPEP 13/4885
US-20150328207-A1 BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 SLC18A2, SLC6A2, SLC18A1 ANPEP 2380/4885RNPEP 2201/4885DNPEP 1957/4885
US-20170298097-A1 Peptide Derivatives and Uses Thereof VIP, IAPP, NGLY1 ANPEP 12/4885RNPEP 58/4885DNPEP 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.