Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 8/20 | 0.36 |
| ▸ | NPY1R | P25929 | 6/20 | 0.36 |
| ▸ | NPY2R | P49146 | 5/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18882585 | 0.95 | NPY4R (0.36) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL20130678 | 0.95 | NPY4R (0.36) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL14031807 | 0.85 | ALOX15 (0.37) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL22215549 | 0.84 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL24703640 | 0.83 | C3AR1 (0.35) | SIRT6SIRT1MEN1KMT2AEPHX1 | |
| SCHEMBL20235709 | 0.83 | KDM4E (0.47) | SIRT6SIRT1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24703697 | 0.83 | C3AR1 (0.35) | SIRT6SIRT1MEN1KMT2AEPHX1 | |
| SCHEMBL13402566 | 0.81 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL24180007 | 0.81 | EPHX1 (0.36) | SIRT6SIRT1MEN1KMT2AEPHX1 | |
| SCHEMBL21503883 | 0.80 | NPY4R (0.38) | NPY4RNPY1RNPY2RNPY5RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626144-B2 | Peptide derivatives and uses thereof | NOSOPHARM (FR) | 2020-04-21 | — | — | US | disclosed |
| US-20170298097-A1 | Peptide Derivatives and Uses Thereof | NOSOPHARM (FR) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626144-B2 | Peptide derivatives and uses thereof | VIP, IAPP, NGLY1 | NPY4R 48/4885NPY1R 71/4885NPY2R 87/4885 |
| US-20170298097-A1 | Peptide Derivatives and Uses Thereof | VIP, IAPP, NGLY1 | NPY4R 48/4885NPY1R 71/4885NPY2R 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.