Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19488554 | 0.87 | SCN10A (0.40) | SCN10AAAK1CACNA1BTGFBR1ROCK2 | |
| SCHEMBL19488306 | 0.84 | SCN10A (0.39) | SCN10AAAK1CACNA1BROCK2MELK | |
| SCHEMBL10200266 | 0.83 | SCN10A (0.50) | SCN10AAAK1ROCK2 | |
| SCHEMBL19488473 | 0.83 | SCN10A (0.39) | SCN10AAAK1ROCK2MELK | |
| SCHEMBL19488792 | 0.81 | SCN10A (0.39) | SCN10AAAK1TGFBR1 | |
| SCHEMBL19488471 | 0.80 | SCN10A (0.40) | SCN10AAAK1 | |
| SCHEMBL16405097 | 0.80 | SCN10A (0.43) | SCN10A | |
| SCHEMBL19488580 | 0.78 | SCN10A (0.37) | SCN10A | |
| SCHEMBL19488293 | 0.78 | AAK1 (0.37) | SCN10AAAK1 | |
| SCHEMBL16938792 | 0.78 | SCN10A (0.43) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |